Which organ system is part of the three primary targets affected in ARS at high doses?

Which organ system is part of the three primary targets affected in ARS at high doses?

• A. Endocrine System
• B. Central Nervous System
• C. Musculoskeletal system
• D. Immune System

Answer: (B)

At high doses, acute radiation syndrome targets three major organ systems: the central nervous system, the hematopoietic (bone marrow) system, and the gastrointestinal tract. The central nervous system is one of these primary targets, so it is the best choice. When radiation is intense, neural tissue, along with the protective barriers and blood vessels in the brain, can be damaged quickly, leading to rapid neurologic symptoms and progression that characterizes the neurovascular aspect of ARS. Endocrine and musculoskeletal systems aren’t considered among the main triad of high-dose ARS targets. The immune effects you see are a consequence of hematopoietic damage, since the bone marrow gives rise to immune cells, but the immune system itself isn’t listed as a separate primary target. The choice reflecting the central nervous system best fits the established pattern of ARS at high doses.

At high doses, acute radiation syndrome targets three major organ systems: the central nervous system, the hematopoietic (bone marrow) system, and the gastrointestinal tract. The central nervous system is one of these primary targets, so it is the best choice. When radiation is intense, neural tissue, along with the protective barriers and blood vessels in the brain, can be damaged quickly, leading to rapid neurologic symptoms and progression that characterizes the neurovascular aspect of ARS.

Endocrine and musculoskeletal systems aren’t considered among the main triad of high-dose ARS targets. The immune effects you see are a consequence of hematopoietic damage, since the bone marrow gives rise to immune cells, but the immune system itself isn’t listed as a separate primary target. The choice reflecting the central nervous system best fits the established pattern of ARS at high doses.